At ManaPlus, we offer private genetic testing to assess your inherited risk for conditions such as cancer and cardiovascular disease. Each test includes a mandatory pre-test consultation with one of our medical professionals, and results are interpreted by expert genetic counsellors to give you a clear, actionable overview of your health risks.

What Is Genetic Testing?

Genetic testing helps identify changes in your DNA that may indicate an increased likelihood of developing certain hereditary diseases. It does not diagnose an illness but can alert you to the presence of genetic variants that could raise your risk of future health problems—allowing for early monitoring, lifestyle changes, or preventive action.

A simple saliva sample is all that’s required.

Should You Consider Cancer Genetic Testing?

You may benefit from testing if:

• A first-degree relative has been diagnosed with cancer

• Multiple family members have had the same or related cancers

• A family member was diagnosed at an unusually young age

• Someone in your family has had more than one cancer type

• You have Ashkenazi Jewish ancestry

• A male relative has had breast cancer

• You’ve had genetic testing in the family that identified a mutation

Genetic Cardiac Testing

Our cardiac test screens 77 genes associated with inherited heart conditions. These insights help you take control of your cardiovascular health through early detection and personalised care planning.

Conditions detected include:

• Cardiomyopathies (heart muscle disorders)

• Arrhythmias (irregular heart rhythm)

• Aortic diseases (aortopathies)

• Familial hypercholesterolemia (inherited high cholesterol)

• Thrombophilia (increased risk of blood clots)

Recommended For People With:

• Unexplained cardiac symptoms

• Sudden or early-onset heart events in the family

• Diagnosed cardiomyopathy or arrhythmias

• Aortic abnormalities

• Genetically elevated cholesterol

• Pulmonary hypertension

Combined Cancer and Cardiac Genetic Testing

Our combined panel gives a complete picture of your inherited health risks. It includes all the genes from both our cancer and cardiac panels, plus additional genes for deeper analysis.

Additional Cancer-Related Genes:

• BRCA1 & BRCA2 (breast and ovarian cancer)

• Lynch Syndrome genes (colon and uterine cancer)

• 23 other cancer-associated genes

Additional Cardiac-Related Genes:

• 3 genes for inherited high cholesterol

• 27 additional cardiac condition-related genes

Mental Health Medication Response:

We also test 2 genes that affect how your body metabolises common mental health medications such as:

• Sertraline

• Citalopram

• Duloxetine

• Amitriptyline

• Escitalopram

• And others

Knowing your genetic compatibility with these medications helps reduce the chance of side effects and increases treatment success.

What Is the Testing Process?

1. Consultation – You will speak to a ManaPlus doctor to discuss what the test involves and what the results could mean.

2. Sample Collection – We will send you a kit including a saliva collection tube, instructions, and a prepaid return envelope.

3. Testing – Your sample will be analysed at a certified UK laboratory.

4. Results & Support – Results are typically ready within 3 to 4 weeks. A medical professional will explain your results and, if needed, arrange follow-up care or referrals.

You must avoid eating, drinking, chewing gum, or smoking for 30 minutes before taking your sample.

Why Choose ManaPlus.co.uk?

Discreet and confidential testing

Fast, accurate results

Comprehensive medical support

Accessible home testing options

Partnerships with UK health experts

Your health and peace of mind are our mission. If you need support following a positive STI result, contact ManaPlus.co.uk today for expert advice, treatment, and ongoing care.